Manage your Migraine and Epilespy
Topiramate is used alone or with other medications to prevent and control seizures(epilepsy). This medication is also used to prevent migraine headache and decrease how often you get them. Topiramate will not treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (such as by taking pain medication, lying down in a dark room).
Pimate (Topiramate) in the Treatment of Epilepsy
Epilepsy is a disease in which repeated seizures occured due to electrical discharges in the brain. Most seizures can be controlled by a single anti-epileptic drug. Unfortunately, some people need more than one anti-epileptic preparation to control seizures, especially if they come from one area (focal epilepsy), not the entire brain. Seizure medication Pimate is used to prevent seizures without neuropsychiatric and somatic side effects and provide pedagogical, professional and social adaptation of the patient. Today, there are two points of view on topiramate for seizures. One of them suggests that anti-epileptic treatment, suppressing epileptic neuronal activity, hinders the progression of the epileptic process, and if successful, contributes to its reverse development. The second point of view treats epilepsy as a stable dynamic state of imbalance in neurotransmitter systems with a predominance of neuronal excitation over inhibition, resulting in hypersynchronous discharges that disrupt psychic, sensory and motor processes and manifest clinically epileptic seizures. It turns out that Pi mate (Topiramate) do not treat epilepsy but restores the balance of inhibitory and excitatory processes in the brain, blocks epileptic hypersynchronous discharges and affects the very pathogenetic basis of the disease, like replacement therapy with dopaminergic agents in Parkinson’s disease. Pimate produces a mixed balanced effect that allows it to be administered to persons with different types of mental disorders. Due to the combination of the five main mechanisms of anticonvulsant action, Pimate (Topiramate) is effective in the treatment of a ny type of seizure, including polyfoca I and resistant to other therapy, therefore, with Topa max therapy, it is not necessary to determine the nature of epileptic seizures.
Pimate (Topiramate) in the Treatment of Migraine
Although the drug Topiramate initially was developed for the treatment of epilepsy and received its first US Food and Drug Administration (FDA) approval for that purpose, it subsequently was shown to be effective for the prevention of migraine headaches and is FDA approved for that indication as well. Migraine and Epilepsy share a considerable number of biologic and clinical features, and it follows that certain of the newer anti-epileptic drugs which are effective for the prevention of migraine attacks as well as seizures. Precisely how Topiramate prevents migraine is unclear, but generally speaking, it appears to reduce the genetically derived brain hyperexcitability that provokes migraine attacks in susceptible individuals.
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